Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510391 | 0.82 | F10 (0.46) | F10NPY2RCNR2MEN1KMT2A | |
| SCHEMBL4000970 | 0.81 | F10 (0.66) | F10CNR2 | |
| SCHEMBL4459582 | 0.80 | F10 (0.61) | F10MEN1KMT2APOLBMAPT | |
| SCHEMBL5506228 | 0.76 | NPY2R (0.41) | F10NPY2RCNR2WDR5MAPT | |
| SCHEMBL5511183 | 0.75 | NPC1 (0.41) | F10NPY2RCNR2CNR1WDR5 | |
| SCHEMBL5505029 | 0.74 | WDR5 (0.41) | F10NPY2RCNR2CNR1MEN1 | |
| SCHEMBL5514263 | 0.73 | F10 (0.53) | F10NPY2RCNR2CNR1 | |
| SCHEMBL5568419 | 0.73 | NPY2R (0.42) | F10NPY2RCNR2CNR1WDR5 | |
| SCHEMBL5562241 | 0.72 | NPY2R (0.41) | F10NPY2RCNR2CNR1WDR5 | |
| SCHEMBL29653575 | 0.71 | F10 (0.62) | F10CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |