Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047717 | 1.00 | MMP2 (0.44) | MMP2GRIN2BGRIN1GRIN2AGRIN2D | |
| SCHEMBL5047712 | 1.00 | MMP2 (0.44) | MMP2GRIN2BGRIN1GRIN2AGRIN2D | |
| SCHEMBL5974310 | 0.89 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL5505091 | 0.89 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL5502026 | 0.89 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL5133156 | 0.88 | HTR7 (0.42) | GRIN2BGRIN1HTR7MEN1KMT2A | |
| SCHEMBL5133153 | 0.88 | HTR7 (0.42) | GRIN2BGRIN1HTR7MEN1KMT2A | |
| SCHEMBL14300258 | 0.86 | GRIN1 (0.41) | GRIN2BGRIN1HTR7MEN1KMT2A | |
| SCHEMBL5041992 | 0.86 | GRIN1 (0.41) | GRIN2BGRIN1HTR7MEN1KMT2A | |
| SCHEMBL5041768 | 0.86 | GRIN1 (0.41) | GRIN2BGRIN1HTR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189886-B1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-01-04 | — | — | EP | claimed |
| US-20050260577-A1 | Detection of neurodegenerative disorders | POWMRI LIMITED (AU) | 2005-11-24 | — | — | US | claimed |
| EP-1189886-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-27 | — | — | EP | claimed |
| US-6310213-B1 | GOOD AFFITITY TO THE NMDA RECEPTOR AND THEY ARE THEREFORE USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | HOFFMANN-LA ROCHE INC. | 2001-10-30 | — | — | US | claimed |
| WO-2000075109-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-14 | — | — | WO | claimed |
| EP-0233299-B1 | OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | claimed |
| US-4855374-A | Optical resin from diallyl esters | NIPPON OIL AND FATS CO., LTD. (JP) | 1989-08-08 | — | — | US | claimed |
| EP-0233299-A1 | Optical resin and process for preparing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-08-26 | — | — | EP | claimed |
| JP-57116302-A | — | — | None | — | — | JP | disclosed |
| EP-3187530-B1 | CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER MATERIAL | ZEON CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| EP-3184585-B1 | CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT | ZEON CORP (JP) | 2020-11-25 | — | — | EP | disclosed |
| US-10428208-B2 | Cross-linkable nitrile rubber composition and cross-linked rubber | ZEON CORPORATION (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3208302-B1 | CROSSLINKABLE NITRILE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT | ZEON CORP (JP) | 2019-09-25 | — | — | EP | disclosed |
| EP-3206872-B1 | ANTI-FOG COATINGS AND METHODS | HONEYWELL INT INC (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-0278060-A2 | Anti-reflection optical article and process of producing the same | TORAY INDUSTRIES, INC. (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0233299-A1 | Optical resin and process for preparing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-08-26 | — | — | EP | disclosed |
| US-4436772-A | ZINC PAINTS, POLYMERS | DAI NIPPON TORYO CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| JP-S57116302-A | SYNTHETIC RESIN LENS | SEIKO EPSON CORP | 1982-07-20 | — | — | JP | disclosed |
| US-4211823-A | Tintable coatings and articles having such coatings | TORAY INDUSTRIES, INC. (JP) | 1980-07-08 | — | — | US | disclosed |
| US-3949021-A | Cross-linked n-vinyl pyrrolidone polymer composition suitable for contact lenses | TORAY INDUSTRIES, INC. (JA) | 1976-04-06 | — | — | US | disclosed |