Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052236 | 0.86 | — | — | |
| SCHEMBL7166020 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL325418 | 0.82 | CES1 (0.44) | GPR84FFAR1FFAR4 | |
| SCHEMBL5693411 | 0.80 | LMNA (0.41) | — | |
| SCHEMBL4754540 | 0.78 | CES2 (0.48) | GPR84FFAR1FFAR4 | |
| SCHEMBL28342850 | 0.76 | — | — | |
| SCHEMBL11115709 | 0.75 | — | — | |
| SCHEMBL5693550 | 0.74 | — | — | |
| SCHEMBL30763338 | 0.74 | CES2 (0.38) | — | |
| Ammonia Solution, Strong SCHEMBL28149509 | 0.74 | CES2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575359-B2 | Acid-sensitive linkers for drug delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110053878-A1 | ACID-SENSITIVE LINKERS FOR DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2007114946-A2 | ACID-SENSITIVE LINKERS FOR DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053878-A1 | ACID-SENSITIVE LINKERS FOR DRUG DELIVERY | CD44, MSN, ABCC1 | CAMK2A 1567/4885GPR84 1275/4885FFAR1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.