Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | SAT1 | P21673 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501993 | 0.71 | CNR2 (0.32) | CNR2TDP1 | |
| SCHEMBL6009077 | 0.71 | CNR2 (0.32) | CNR2TDP1 | |
| SCHEMBL6009868 | 0.66 | HDAC6 (0.33) | CNR2CNR1 | |
| SCHEMBL6009419 | 0.66 | HDAC6 (0.33) | CNR2CNR1 | |
| SCHEMBL6009995 | 0.65 | HDAC6 (0.35) | CNR2CNR1 | |
| SCHEMBL6009965 | 0.65 | HDAC6 (0.35) | CNR2CNR1 | |
| SCHEMBL10107696 | 0.63 | SAT1 (0.35) | SAT1TDP1 | |
| SCHEMBL5504916 | 0.63 | ADH1B (0.36) | CNR2CNR1 | |
| SCHEMBL1046192 | 0.63 | LIPA (0.34) | SAT1TDP1 | |
| SCHEMBL10766978 | 0.62 | INPP5A (0.41) | SAT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |