Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502040 | 0.81 | RECQL (0.35) | DRD2SLC18A3ALDH1A1 | |
| SCHEMBL26157260 | 0.67 | KDM1A (0.44) | HRH1TLR9TLR8TLR7KDM1A | |
| SCHEMBL6643569 | 0.67 | HRH1 (0.38) | HRH1CCNT1CDK9MAPK11MAPK14 | |
| SCHEMBL22415909 | 0.67 | CCNT1 (0.39) | CCNT1CDK9MAPK11MAPK14TLR9 | |
| SCHEMBL30010674 | 0.67 | CCNT1 (0.39) | CCNT1CDK9MAPK11MAPK14TLR9 | |
| SCHEMBL18776398 | 0.67 | KDM1A (0.42) | HRH1MAPK11MAPK14KDM1AMAP3K12 | |
| SCHEMBL8096432 | 0.66 | DRD2 (0.68) | KDM1ADRD2SLC18A3 | |
| SCHEMBL21936084 | 0.66 | NTRK1 (0.43) | HRH1CCNT1CDK9TLR9TLR8 | |
| SCHEMBL22415828 | 0.66 | DRD2 (0.50) | CCNT1CDK9DRD2SLC18A3ALDH1A1 | |
| SCHEMBL30010274 | 0.66 | DRD2 (0.50) | CCNT1CDK9DRD2SLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |