SCHEMBL5506264

SCHEMBL5506264

C=CC(N)NC1CCCC[N]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948056 0.75
SCHEMBL2781515 0.71
SCHEMBL947063 0.70 NOS3 (0.34) NOS1NOS2
SCHEMBL5550433 0.70 ALDH1A1 (0.36)
SCHEMBL946194 0.68 NOS3 (0.33) NOS1NOS2
SCHEMBL4511579 0.65 NOS1 (0.33) NOS1NOS2
SCHEMBL4724571 0.65 KDM4E (0.43) NOS1NOS2
SCHEMBL2781581 0.65
SCHEMBL4720878 0.64 EPHX1 (0.35) NOS1NOS2
SCHEMBL4722017 0.63 CYP2D6 (0.31) NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740574-B1 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES OTSUKA PHARMA CO LTD (JP) 2007-06-27 EP claimed