Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515208 | 0.91 | MAPT (0.38) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5516043 | 0.87 | POLB (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1HPGD | |
| SCHEMBL5517754 | 0.84 | POLB (0.36) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL5270824 | 0.84 | PTPN1 (0.37) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5573968 | 0.83 | HPGD (0.43) | ALOX5CSF1RCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5508283 | 0.83 | TP53 (0.42) | ALOX5CSF1RCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5519196 | 0.82 | CSF1R (0.38) | ALOX5CSF1RCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL5505105 | 0.82 | ALOX5 (0.43) | ALOX5CSF1RCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5503249 | 0.81 | KDM4E (0.37) | CSF1RCYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL5266671 | 0.81 | POLB (0.41) | ALOX5CYP1A2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |