Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503574 | 0.90 | MEN1 (0.39) | TP53MDM2ALOX5ALDH1A1KMT2A | |
| SCHEMBL5511414 | 0.88 | TP53 (0.41) | TP53MDM2ALOX5ALDH1A1LMNA | |
| SCHEMBL5506207 | 0.88 | TP53 (0.41) | TP53MDM2ALOX5ALDH1A1LMNA | |
| SCHEMBL5516043 | 0.84 | POLB (0.43) | TP53ALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL5503249 | 0.83 | KDM4E (0.37) | TP53ALDH1A1KMT2ACSF1RHPGD | |
| SCHEMBL5506461 | 0.83 | ALOX5 (0.40) | TP53MDM2ALOX5ALDH1A1LMNA | |
| SCHEMBL5504449 | 0.83 | ALOX5 (0.39) | TP53MDM2ALOX5KMT2ACSF1R | |
| SCHEMBL5519196 | 0.82 | CSF1R (0.38) | TP53MDM2ALOX5ALDH1A1LMNA | |
| SCHEMBL5517754 | 0.82 | POLB (0.36) | TP53ALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL5270824 | 0.81 | PTPN1 (0.37) | ALOX5ALDH1A1KMT2APTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |