Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 12/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783595 | 0.85 | RBP4 (0.58) | RBP4DRD2 | |
| SCHEMBL5501124 | 0.85 | DRD2 (0.52) | RBP4DRD2SLC6A4 | |
| SCHEMBL2783494 | 0.83 | RBP4 (0.43) | RBP4 | |
| SCHEMBL5533630 | 0.82 | DRD2 (0.39) | RBP4DRD2SLC6A4DCUN1D1 | |
| SCHEMBL5502093 | 0.82 | DRD2 (0.39) | RBP4DRD2SLC6A4 | |
| SCHEMBL2781457 | 0.82 | DRD2 (0.56) | RBP4DRD2SLC6A4 | |
| SCHEMBL5499738 | 0.81 | DRD2 (0.38) | RBP4DRD2SLC6A4 | |
| SCHEMBL2782833 | 0.80 | RBP4 (0.54) | RBP4DRD2 | |
| SCHEMBL5502922 | 0.80 | DRD2 (0.39) | RBP4DRD2SLC6A4 | |
| SCHEMBL5502925 | 0.79 | RBP4 (0.38) | RBP4DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | claimed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |