Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 9/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502922 | 0.86 | DRD2 (0.39) | RBP4DRD2DRD3HTR2AHRH2 | |
| SCHEMBL5506986 | 0.79 | RBP4 (0.47) | RBP4DRD2SLC6A4 | |
| SCHEMBL5502093 | 0.76 | DRD2 (0.39) | RBP4DRD2DRD3HRH2SLC6A4 | |
| SCHEMBL2782455 | 0.76 | RBP4 (0.47) | RBP4DRD2DRD3HTR2AKDM1A | |
| SCHEMBL2782898 | 0.76 | DRD2 (0.45) | RBP4DRD2DRD3HTR2AKDM1A | |
| SCHEMBL5502725 | 0.76 | DRD2 (0.40) | RBP4DRD2DRD3HTR2AHRH2 | |
| SCHEMBL3774685 | 0.75 | DRD4 (0.41) | DRD2DRD3SLC6A4GRM2 | |
| SCHEMBL3766106 | 0.75 | SIGMAR1 (0.44) | DRD2DRD3SLC6A4HTR1AGRM2 | |
| SCHEMBL5501370 | 0.75 | DRD2 (0.43) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL5499738 | 0.74 | DRD2 (0.38) | RBP4DRD2DRD3HTR2AHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |