SCHEMBL5507102

SCHEMBL5507102

CCCCCCc1sccc1C=CC=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.36
EPAS1 Q99814 1/20 0.36
GPR35 Q9HC97 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TP53 P04637 3/20 0.33
HSP90AA1 P07900 2/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
G6PD P11413 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
PLA2G4A P47712 2/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
APAF1 O14727 1/20 0.32
RGS12 O14924 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2082912 0.82 HIF1A (0.40) HIF1AEPAS1GPR35ALDH1A1TP53
Ethylene SCHEMBL8219135 0.80 HIF1A (0.38) HIF1AEPAS1GPR35ALDH1A1TP53
SCHEMBL28801300 0.78 THRB (0.37) HIF1AEPAS1GPR35ALDH1A1TP53
SCHEMBL30725645 0.72 LIPG (0.47) HSD17B10ALOX15MAPTTHRATHRB
SCHEMBL2941319 0.72 LIPG (0.47) HSD17B10ALOX15MAPTTHRATHRB
SCHEMBL152797 0.72 LIPG (0.47) HSD17B10ALOX15MAPTTHRATHRB
SCHEMBL28904223 0.72 LTB4R (0.44) HIF1AGPR35ALDH1A1TP53HSP90AA1
SCHEMBL2939139 0.70 CDK4 (0.47) THRATHRBCDK4CCND1PTGS2
SCHEMBL450217 0.70 CDK4 (0.47) THRATHRBCDK4CCND1PTGS2
SCHEMBL15648187 0.70 LTB4R (0.49) GPR35TP53TSHRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620424-A4 IMPROVED JASMINE AROMACHEMICALS FLEXITRAL INC (US) 2007-10-31 EP disclosed
EP-1620424-A2 IMPROVED JASMINE AROMACHEMICALS Flexitral Inc. (US) 2006-02-01 EP disclosed
WO-2004067481-A2 IMPROVED JASMINE AROMACHEMICALS FLEXITRAL, INC. (US) 2004-08-12 WO disclosed