Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080415 | 0.84 | MAPT (0.53) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9040295 | 0.81 | MAPT (0.51) | MAPTNPC1HTTMAPK1KDM4E | |
| SCHEMBL9274950 | 0.81 | MEN1 (0.61) | MAPTNPC1HTTMAPK1KDM4E | |
| SCHEMBL11575893 | 0.81 | KEAP1 (0.58) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL10964252 | 0.81 | NOS2 (0.60) | MAPTNPC1HTTMAPK1KDM4E | |
| SCHEMBL11575664 | 0.81 | KDM4E (0.58) | MAPTNPC1HTTMAPK1KDM4E | |
| SCHEMBL8323160 | 0.80 | MAPT (0.44) | MAPTNPC1HTTMAPK1KDM4E | |
| SCHEMBL4187193 | 0.80 | RAB9A (0.62) | MAPTNPC1HTTKDM4EHPGD | |
| SCHEMBL8397350 | 0.80 | RAB9A (0.53) | MAPTNPC1HTTMAPK1KDM4E | |
| P-Xylene SCHEMBL11798546 | 0.80 | MEN1 (0.59) | MAPTNPC1HTTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579241-B | Thermosensitive recording medium | 王子控股株式会社 | 2018-10-16 | — | — | CN | disclosed |
| CN-104995033-B | Thermosensitive recording medium | 王子控股株式会社 | 2017-10-13 | — | — | CN | disclosed |
| WO-2012154880-A1 | PROTEOSTASIS REGULATORS FOR TREATING CYSTIC FIBROSIS AND OTHER PROTEIN MISFOLDING DISEASES | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-1771816-A1 | A MULTIFUNCTION, DIRECT THERMAL RECORDING MATERIAL | Kanzaki Specialty Papers Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006005000-A1 | A MULTIFUNCTION, DIRECT THERMAL RECORDING MATERIAL | KANZAKI SPECIALTY PAPERS INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| CN-1134517-C | Disazo pigment composition and printing ink | 3M | 2004-01-14 | — | — | CN | disclosed |
| CN-1175607-A | Tetrazo pigment composition and printing ink | DAINIPPON INK & CHEMICALS (JP) | 1998-03-11 | — | — | CN | disclosed |
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |