SCHEMBL5507533

SCHEMBL5507533

COC(=O)c1ccc(CN(O)Cc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.61
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
GAA P10253 1/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CYP4A11 Q02928 2/20 0.56
CYP4F2 P78329 1/20 0.54
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
MAPT P10636 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5983459 0.98 LOXL2 (0.59) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL8781971 0.87 LOXL2 (0.59) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL5642409 0.85 LOXL2 (0.58) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL5067508 0.85 LOXL2 (0.61) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL8781908 0.82 LOXL2 (0.54) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL5185961 0.81 LOXL2 (0.58) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL5068516 0.81 HDAC8 (0.65) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL23423391 0.80 LOXL2 (0.56) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL15392053 0.80 MAPT (0.61) LOXL2TSHRALDH1A1KDM4ENPC1
SCHEMBL10397250 0.80 MAPT (0.61) LOXL2TSHRALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4668727-A Ester substituted benzylhydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1987-05-26 US claimed
EP-1572817-B1 INK-JET INK AND RECORDING MATERIAL CIBA SC HOLDING AG (CH) 2007-03-21 EP disclosed
EP-0686874-B1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK CO (US) 1997-12-17 EP disclosed
US-5660974-A EXPOSING, DEVELOPING EASTMAN KODAK COMPANY (US) 1997-08-26 US disclosed
EP-0686874-A1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK COMPANY (US) 1995-12-13 EP disclosed
US-4668727-A Ester substituted benzylhydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1987-05-26 US disclosed