SCHEMBL8781908

SCHEMBL8781908

COC(=O)c1ccc(CN(O)C(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.54
CYP4A11 Q02928 2/20 0.50
HSP90AA1 P07900 1/20 0.49
RAB9A P51151 1/20 0.49
CYP4F2 P78329 1/20 0.49
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HDAC1 Q13547 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
MAPT P10636 3/20 0.47
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397101 0.85 HDAC1 (0.66) LOXL2CYP4A11HSP90AA1RAB9ACYP4F2
SCHEMBL5507533 0.82 LOXL2 (0.61) LOXL2CYP4A11RAB9ACYP4F2KDM4E
SCHEMBL8781971 0.81 LOXL2 (0.59) LOXL2CYP4A11HSP90AA1RAB9ACYP4F2
Hydrochloric Acid SCHEMBL5983459 0.81 LOXL2 (0.59) LOXL2CYP4A11RAB9ACYP4F2KDM4E
SCHEMBL8667684 0.81 ALDH1A1 (0.52) HSP90AA1ALDH1A1TSHRHDAC1HDAC8
SCHEMBL5068516 0.79 HDAC8 (0.65) LOXL2CYP4A11RAB9ACYP4F2KDM4E
SCHEMBL5642409 0.79 LOXL2 (0.58) LOXL2CYP4A11RAB9ACYP4F2KDM4E
SCHEMBL5067508 0.79 LOXL2 (0.61) LOXL2CYP4A11HSP90AA1RAB9ACYP4F2
SCHEMBL15392053 0.78 MAPT (0.61) LOXL2CYP4A11RAB9AKDM4EALDH1A1
SCHEMBL27220639 0.78 LOXL2 (0.56) LOXL2CYP4A11RAB9ACYP4F2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686874-B1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK CO (US) 1997-12-17 EP disclosed
US-5660974-A EXPOSING, DEVELOPING EASTMAN KODAK COMPANY (US) 1997-08-26 US disclosed
EP-0686874-A1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK COMPANY (US) 1995-12-13 EP disclosed