Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506790 | 0.92 | L3MBTL3 (0.36) | L3MBTL3HRH3CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL13788009 | 0.73 | ALDH1A1 (0.38) | L3MBTL3ALDH1A1KDM4EHRH3CYP3A4 | |
| SCHEMBL4388125 | 0.68 | GAA (0.45) | L3MBTL3ALDH1A1KDM4EL3MBTL1EPHX1 | |
| SCHEMBL4383438 | 0.65 | HRH3 (0.35) | L3MBTL3ALDH1A1HRH3CYP3A4CYP2C9 | |
| SCHEMBL4383440 | 0.64 | L3MBTL3 (0.44) | L3MBTL3ALDH1A1KDM4EHRH3CYP3A4 | |
| SCHEMBL4391427 | 0.64 | L3MBTL3 (0.37) | L3MBTL3HRH3CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL4391600 | 0.64 | L3MBTL3 (0.37) | L3MBTL3HRH3CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL4385702 | 0.62 | L3MBTL3 (0.36) | L3MBTL3HRH3CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL3774303 | 0.61 | ALDH1A1 (0.76) | L3MBTL3ALDH1A1KDM4EHRH3L3MBTL1 | |
| SCHEMBL5502785 | 0.61 | HRH3 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |