Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377645 | 0.76 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL3478592 | 0.72 | CDK1 (0.50) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL26752005 | 0.69 | DUT (0.34) | — | |
| SCHEMBL2179785 | 0.69 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL107915 | 0.69 | PDPK1 (0.40) | — | |
| SCHEMBL7063134 | 0.65 | PDPK1 (0.37) | CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL9675388 | 0.65 | POLB (0.55) | — | |
| SCHEMBL6888654 | 0.64 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1251786 | 0.63 | — | — | |
| SCHEMBL3964705 | 0.63 | PDPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977767-B1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2007-09-19 | — | — | EP | disclosed |