SCHEMBL107915

SCHEMBL107915

[CH2]Cc1nc2nc(N)nc(N)c2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.40
GDA Q9Y2T3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478592 0.81 CDK1 (0.50)
SCHEMBL7063134 0.80 PDPK1 (0.37) PDPK1GDA
SCHEMBL1377645 0.78 PI4KA (0.49)
SCHEMBL6684462 0.74 PI4KA (0.60)
SCHEMBL2179785 0.74 PI4KA (0.46) PDPK1GDA
SCHEMBL27648253 0.73 PNP (0.61)
SCHEMBL3396382 0.73 PNP (0.52) PDPK1GDA
SCHEMBL1766004 0.69 PDPK1 (0.44) PDPK1GDA
SCHEMBL16513157 0.69 PDPK1 (0.44) PDPK1GDA
SCHEMBL1705024 0.69 PDPK1 (0.44) PDPK1GDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230108350-A1 METHOD FOR PRODUCING PNA OLIGOMER IN SOLUTION PROCESS SEASUNBIO MATERIALS (KP) 2023-04-06 US claimed
CN-114901673-A Method for preparing solution phase peptide nucleic acid oligomer 海阳生物材料有限公司 2022-08-12 CN claimed
US-11118215-B2 Method for obtaining structural information concerning an encoded molecule and method for selecting compounds NUEVOLUTION A/S (DK) 2021-09-14 US claimed
US-20210163541-A1 Method for Preparing PNA Oligomer SEASUNBIO MATERIALS (KR) 2021-06-03 US claimed
US-11001835-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2021-05-11 US claimed
US-20200263238-A1 DETECTION OF MYCOPLASMA IN CELL CULTURES AND CELL CULTURE DERIVED BIOLOGICALS AKRON BIOTECHNOLOGY LLC (US) 2020-08-20 US claimed
US-10730906-B2 Multi-step synthesis of templated molecules NUEVOLUTIONS A/S (DK) 2020-08-04 US claimed
US-10731151-B2 Method for synthesising templated molecules NUEVOLUTION A/S (DK) 2020-08-04 US claimed
US-10077440-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2018-09-18 US claimed
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 EP claimed
EP-1282639-A2 POLYAMIDE NUCLEIC ACID DERIVATIVES, AGENTS AND METHODS FOR PRODUCING THE SAME Aventis Pharma Deutschland GmbH (DE) 2003-02-12 EP claimed
US-20030022172-A1 Polyamide nucleic acid derivatives and agents and processes for preparing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2003-01-30 US claimed
US-20020187473-A1 Peptide nucleic acid for use in the treatment skin, inflammatory and vitiligo disorders SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2002-12-12 US claimed
US-6465650-B1 INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-10-15 US claimed
EP-0672677-B1 Polyamide-oligonucleotide derivatives, their production and use AVENTIS PHARMA GMBH (DE) 2002-07-03 EP claimed
US-6388061-B1 INCLUDES RUTHENIUM TRIS(BIPYRIDYL) LABEL BONDED TO THE NITROGEN BASE DAKO A/S (DK) 2002-05-14 US claimed
WO-2001079249-A2 PEPTIDE NUCLEIC ACID DERIVATIVES WITH A NEGATIVE CHARGE, AGENTS AND METHODS FOR PRODUCING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-10-25 WO claimed
EP-1113021-A2 Polyamide-oligonucleotide derivatives, their production and use Aventis Pharma Deutschland GmbH (DE) 2001-07-04 EP claimed
EP-0672701-B1 PNA-synthesis using a base labile aminoprotecting group HOECHST AG (DE) 1999-07-28 EP claimed
EP-0672700-B1 PNA-synthesis using an aminoprotecting group which is labile against weak acids HOECHST AG (DE) 1999-06-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163541-A1 Method for Preparing PNA Oligomer NCL, NOD1, POLI PDPK1 4061/4885GDA 394/4885
US-20230108350-A1 METHOD FOR PRODUCING PNA OLIGOMER IN SOLUTION PROCESS NCL, POLI, RNGTT PDPK1 2571/4885GDA 380/4885
US-10731151-B2 Method for synthesising templated molecules FGB, ILK, TBCB PDPK1 4426/4885GDA 898/4885
US-20030022172-A1 Polyamide nucleic acid derivatives and agents and processes for preparing them PHAX, POLRMT, PNKP PDPK1 640/4885GDA 165/4885
US-10730906-B2 Multi-step synthesis of templated molecules COASY, DAP3, EMG1 PDPK1 3573/4885GDA 861/4885
US-20020187473-A1 Peptide nucleic acid for use in the treatment skin, inflammatory and vitiligo disorders SSB, POLI, POLRMT PDPK1 299/4885GDA 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.