Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519482 | 1.00 | RIPK1 (0.44) | RIPK1SUCNR1CETPBDKRB1RAB9A | |
| SCHEMBL582810 | 1.00 | RIPK1 (0.44) | RIPK1SUCNR1CETPBDKRB1RAB9A | |
| SCHEMBL27688257 | 0.85 | RIPK1 (0.45) | RIPK1BDKRB1RAB9ANPC1GAA | |
| SCHEMBL5513992 | 0.84 | KMT2A (0.46) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL582729 | 0.84 | P2RX7 (0.43) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL582826 | 0.84 | KMT2A (0.46) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL5517336 | 0.84 | P2RX7 (0.43) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL5517353 | 0.84 | KMT2A (0.46) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL5509355 | 0.84 | P2RX7 (0.43) | RIPK1SUCNR1CETPMEN1KMT2A | |
| SCHEMBL5524961 | 0.83 | AKR1B1 (0.42) | RIPK1SUCNR1CETPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268153-B2 | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators | MERCK & CO., INC. (US) | 2007-09-11 | — | — | US | claimed |