Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508093 | 0.84 | USP2 (0.34) | USP2TSHRALDH1A1POLBTHRB | |
| SCHEMBL5502049 | 0.83 | HRH3 (0.37) | USP2TSHRHRH3 | |
| SCHEMBL5501800 | 0.83 | ALDH1A1 (0.39) | USP2TSHRALDH1A1POLBTHRB | |
| SCHEMBL5501716 | 0.82 | HRH3 (0.36) | USP2TSHRHRH3 | |
| SCHEMBL5502494 | 0.82 | CXCR4 (0.42) | USP2TSHRHRH3MAOBHRH2 | |
| SCHEMBL5504004 | 0.82 | HRH3 (0.41) | USP2TSHRALDH1A1POLBTHRB | |
| SCHEMBL5508190 | 0.81 | HRH3 (0.44) | HRH3MAOBHRH2HRH1HTR7 | |
| SCHEMBL5502187 | 0.80 | HRH3 (0.44) | USP2TSHRALDH1A1POLBTHRB | |
| SCHEMBL5502432 | 0.80 | HRH3 (0.41) | USP2TSHRALDH1A1POLBTHRB | |
| SCHEMBL5504843 | 0.80 | SIGMAR1 (0.44) | POLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |