Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502432 | 0.93 | HRH3 (0.41) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5506694 | 0.93 | PAOX (0.36) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5505457 | 0.90 | PAOX (0.37) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5504004 | 0.90 | HRH3 (0.41) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5507633 | 0.89 | KDM4E (0.45) | ALDH1A1POLBSMN1; SMN2HRH3KDM4E | |
| SCHEMBL5504843 | 0.89 | SIGMAR1 (0.44) | POLBHRH3KDM4ESIGMAR1TDP1 | |
| SCHEMBL5502187 | 0.89 | HRH3 (0.44) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5508190 | 0.86 | HRH3 (0.44) | HRH3MAOBKDM4EHTR7 | |
| SCHEMBL5508030 | 0.84 | MAOA (0.40) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5501716 | 0.84 | HRH3 (0.36) | HRH3USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |