Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756827 | 0.98 | MAOA (0.35) | MAOAMAOBKDM4EALDH1A1MEN1 | |
| SCHEMBL57274 | 0.98 | MAOA (0.35) | MAOAMAOBKDM4EALDH1A1MEN1 | |
| Succinic Acid SCHEMBL7699826 | 0.84 | HTT (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL11556600 | 0.84 | MAOA (0.32) | MAOAMAOBKDM4EALDH1A1MEN1 | |
| SCHEMBL4393423 | 0.81 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL30407118 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6337417 | 0.75 | POLB (0.46) | MAOAMAOBMAPT | |
| SCHEMBL293045 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30485934 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30096256 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737847-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | Torrent Pharmaceuticals Ltd (IN) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006025070-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-03-09 | — | — | WO | disclosed |