SCHEMBL57274

SCHEMBL57274

OC1C=Cc2ccccc2O1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
HPGD P15428 1/20 0.33
P2RY6 Q15077 1/20 0.31
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756827 1.00 MAOA (0.35) MAOAMAOBKDM4EALDH1A1MEN1
Methane SCHEMBL5508429 0.98 MAOA (0.34) MAOAMAOBKDM4EALDH1A1MEN1
Succinic Acid SCHEMBL7699826 0.86 HTT (0.41) KDM4EALDH1A1HPGD
SCHEMBL11556600 0.86 MAOA (0.32) MAOAMAOBKDM4EALDH1A1MEN1
SCHEMBL4393423 0.82 MAOA (0.33) MAOAMAOB
SCHEMBL6238159 0.78 HTR2C (0.34) KDM4EALDH1A1HPGDHTR2CHTR2B
SCHEMBL30407118 0.77 KDM4E (0.35) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL6337417 0.76 POLB (0.46) MAOAMAOBMAPT
SCHEMBL293045 0.76 KDM4E (0.37) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL30096256 0.76 KDM4E (0.38) KDM4EALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735363-A Treatment method of chrome tanning waste liquid 嘉兴学院 2021-12-03 CN claimed
EP-3381904-B1 NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND MITSUBISHI TANABE PHARMA CORP (JP) 2021-07-28 EP claimed
CN-112206350-A Pretreatment method of bovine pericardial tissue for manufacturing biological valve 张飞 2021-01-12 CN claimed
US-10268117-B2 Top-layer membrane formation composition and method for forming resist pattern using same AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2019-04-23 US claimed
US-20170090288-A1 TOP-LAYER MEMBRANE FORMATION COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING SAME AZ ELECTRONIC MATERIALS S.À R.L. (LU) 2017-03-30 US claimed
EP-1182183-B1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO (JP) 2009-12-09 EP claimed
US-6605667-B1 1,1-disubstituted ethylene monomers such as alpha-cyano-acrylates; storage stability CLOSURE MEDICAL CORPORATION 2003-08-12 US claimed
WO-2002020069-A2 ANTIOXIDANT ENRICHED ADHESIVE COMPOSITIONS AND STORAGE CONTAINERS THEREFOR CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO claimed
EP-0443533-B1 Positive photoresist composition FUJI PHOTO FILM CO LTD (JP) 1998-09-30 EP claimed
EP-0485173-A2 Esters and amides of substituted fused ring phenyl acetic acids FGN, INC. (US) 1992-05-13 EP claimed
EP-0443533-A2 Positive photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF COTY INC. 2025-04-24 US disclosed
CN-118290462-A Dual-channel simultaneous detection pH and ONOO-Fluorescent probe of (2), preparation method and application thereof 中国科学院理化技术研究所 2024-07-05 CN disclosed
US-20240197814-A1 MATERIALS AND METHODS FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES OAK CREST INSTITUTE OF SCIENCE 2024-06-20 US disclosed
EP-4308146-A1 MATERIALS AND METHODS FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES Oak Crest Institute of Science (US) 2024-01-24 EP disclosed
EP-0021676-B1 3-METHOXY-2-OXOAZETIDINE DERIVATIVES AND THEIR PRODUCTION Takeda Chemical Industries, Ltd. (JP) 1983-09-14 EP disclosed
US-4108871-A Novel benzopyran derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1978-08-22 US disclosed
US-4049653-A ANALGESICS, ANTIANXIETY AGENTS ABBOTT LABORATORIES (US) 1977-09-20 US disclosed
US-4032540-A BENZOPYRAN DERIVATIVES SCHERING AKTIENGESELLSCHAFT (DT) 1977-06-28 US disclosed
US-3962280-A PROCESS FOR PREPARING BENZOPYRAN DERIVATIVES SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF TRPA1, TRPV1, NAA40 MAOA 1576/4885MAOB 2868/4885KDM4E 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.