Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 8/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044563 | 0.72 | — | — | |
| SCHEMBL5510349 | 0.71 | DHFR (0.33) | DHFRTLR7TLR8 | |
| SCHEMBL5504493 | 0.71 | ADORA2A (0.40) | KDM4EMAPTTLR7TLR8ADORA3 | |
| SCHEMBL6807516 | 0.68 | PI4KA (0.41) | DHFRTLR7TLR8 | |
| SCHEMBL5504392 | 0.67 | MAPT (0.34) | KDM4EMAPTDHFRADORA3ADORA2A | |
| SCHEMBL5616291 | 0.67 | DHFR (0.39) | DHFRTLR7TLR8 | |
| SCHEMBL1703456 | 0.66 | TLR7 (0.57) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL3862404 | 0.63 | TLR8 (0.37) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL3977482 | 0.63 | TLR7 (0.37) | KDM4EMAPTDHFRTLR7TLR8 | |
| Isobutanol SCHEMBL10444099 | 0.63 | KMT2A (0.45) | KDM4EMAPTTLR7TLR8ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850849-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | Coley Pharmaceutical Group, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006091647-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |