SCHEMBL5509024

SCHEMBL5509024

CCCC(Nc1ccccn1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.50
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
FDPS P14324 1/20 0.46
GAA P10253 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
PKM P14618 2/20 0.45
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KDM4E B2RXH2 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511511 0.88 ALDH1A1 (0.51) HTTSMN1; SMN2FDPSGAAALDH1A1
SCHEMBL29416424 0.88 ALDH1A1 (0.51) HTTSMN1; SMN2FDPSGAAALDH1A1
SCHEMBL17241309 0.84 GAA (0.48) FDPSGAAALDH1A1PKMLMNA
SCHEMBL31052773 0.84 GRN (0.46) HTTSMN1; SMN2FDPSGAAALDH1A1
SCHEMBL6381259 0.83 SMN1; SMN2 (0.56) MMEHTTSMN1; SMN2GAAALDH1A1
SCHEMBL6379100 0.83 SMN1; SMN2 (0.56) MMEHTTSMN1; SMN2GAAALDH1A1
SCHEMBL6379107 0.83 SMN1; SMN2 (0.56) MMEHTTSMN1; SMN2GAAALDH1A1
SCHEMBL9600527 0.83 GAA (0.50) HTTSMN1; SMN2FDPSGAAPOLB
SCHEMBL9600519 0.83 GAA (0.50) HTTSMN1; SMN2FDPSGAAPOLB
SCHEMBL31606452 0.82 FDPS (0.44) HTTSMN1; SMN2FDPSGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed