Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600527 | 1.00 | GAA (0.50) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL5828232 | 0.85 | FDPS (0.49) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL5511511 | 0.85 | ALDH1A1 (0.51) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL6657106 | 0.85 | FDPS (0.49) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL29416424 | 0.85 | ALDH1A1 (0.51) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL5939842 | 0.84 | L3MBTL1 (0.59) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL5939834 | 0.84 | L3MBTL1 (0.59) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL5509024 | 0.83 | MME (0.50) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL31606452 | 0.80 | FDPS (0.44) | GAAFDPSNPC1RAB9APKM | |
| SCHEMBL561975 | 0.79 | KDM4E (0.50) | MEN1KMT2ASLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153253-A2 | AROMATIC COMPOUNDS AND METAL COMPLEXES THEREOF | DU PREEZ JAN GYSBERT HERMANUS (ZA) | 2012-11-15 | — | — | WO | disclosed |
| WO-1993020053-A1 | PYRIDYLSERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-14 | — | — | WO | disclosed |
| EP-0079390-B1 | PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-12-27 | — | — | EP | disclosed |
| EP-0079390-A1 | PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-05-25 | — | — | EP | disclosed |