SCHEMBL5509028

SCHEMBL5509028

CCCCN(C(=O)O)c1ccccn1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.55
TSHR P16473 3/20 0.54
OPRM1 P35372 2/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TRPM8 Q7Z2W7 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511513 0.90 POLB (0.57) POLBTSHROPRM1MEN1KMT2A
SCHEMBL14229128 0.86 OPRM1 (0.51) POLBTSHROPRM1MEN1KMT2A
SCHEMBL5508940 0.83 POLB (0.60) POLBTSHRMEN1KMT2ATRPM8
SCHEMBL14200371 0.83 OPRM1 (0.48) POLBTSHROPRM1MEN1KMT2A
SCHEMBL19306196 0.81 TSHR (0.62) POLBTSHRMEN1KMT2ATRPM8
SCHEMBL14543473 0.81 OPRM1 (0.47) POLBTSHROPRM1MEN1KMT2A
SCHEMBL4065147 0.78 ALDH1A1 (0.45) OPRM1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL2892022 0.78 NPC1 (0.61) TSHRMEN1KMT2ATRPM8SMN1; SMN2
SCHEMBL28366068 0.78 CYP2D6 (0.65) SMN1; SMN2LMNAMAPK1
SCHEMBL4806424 0.78 CYP2D6 (0.50) TSHROPRM1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed