Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509135 | 0.86 | DHODH (0.62) | DHODHFFAR4NR4A2RXRARXRB | |
| SCHEMBL5509546 | 0.84 | DHODH (0.52) | DHODHNR4A2SMN1; SMN2 | |
| SCHEMBL5511055 | 0.79 | DHODH (0.54) | DHODHNR4A2SMN1; SMN2 | |
| SCHEMBL5512655 | 0.75 | DHODH (0.56) | DHODH | |
| SCHEMBL5515802 | 0.71 | DHODH (0.61) | DHODHNR4A2 | |
| SCHEMBL502818 | 0.71 | DHODH (1.00) | DHODHNR4A2 | |
| SCHEMBL5521885 | 0.70 | DHODH (0.72) | DHODHNR4A2 | |
| SCHEMBL5517278 | 0.70 | DHODH (0.72) | DHODHNR4A2 | |
| SCHEMBL23580761 | 0.70 | RXRA (0.56) | DHODHFFAR4RXRARXRBSMN1; SMN2 | |
| SCHEMBL1336975 | 0.70 | DHODH (0.79) | DHODHNR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070224672-A1 | Method of Identifying Inhibitors of DHODH | LEBAN JOHANN | 2007-09-27 | — | — | US | disclosed |
| US-7247736-B2 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | DHODH, SQOR, NDUFA5 | DHODH 1/4885FFAR4 4559/4885NR4A2 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.