Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395557 | 0.80 | KIF11 (0.39) | KIF11BACE1HSD17B3CA1MCL1 | |
| SCHEMBL391593 | 0.80 | CES2 (0.45) | KIF11HSD17B3CA1MCL1CA2 | |
| SCHEMBL27255621 | 0.78 | SMN1; SMN2 (0.61) | CA1MCL1APPCA2ERN1 | |
| SCHEMBL5511595 | 0.78 | GAA (0.50) | KIF11HSD17B3CA1MCL1CA12 | |
| SCHEMBL17287119 | 0.76 | SMN1; SMN2 (0.39) | BACE1CA1CA12CA9CA2 | |
| SCHEMBL14421389 | 0.76 | ALDH1A1 (0.38) | KIF11MCL1ERN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28440862 | 0.75 | BACE1 (0.49) | KIF11BACE1ARALDH1A1POLB | |
| SCHEMBL5508465 | 0.74 | KIF11 (0.35) | KIF11BACE1HSD17B3CA1MCL1 | |
| SCHEMBL16784212 | 0.74 | ALDH1A1 (0.36) | KIF11HSD17B3CA1MCL1CA2 | |
| SCHEMBL16334744 | 0.72 | APP (0.35) | KIF11BACE1HSD17B3APPPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |