Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | AMD1 | P17707 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509894 | 1.00 | MEN1 (0.42) | MEN1KMT2AADORA3PI4KAPI4K2B | |
| SCHEMBL5504146 | 0.88 | PI4KA (0.41) | ADORA3PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5504141 | 0.88 | PI4KA (0.41) | ADORA3PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5504161 | 0.87 | TSHR (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5509065 | 0.87 | TSHR (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5504164 | 0.87 | TSHR (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5509613 | 0.87 | ADORA3 (0.49) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5509240 | 0.87 | TSHR (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5513305 | 0.86 | ADORA2A (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL5513298 | 0.86 | ADORA2A (0.52) | MEN1KMT2AADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |