Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419265 | 0.89 | P2RX1 (0.41) | KCNJ11CNR2MAPTALDH1A1HSD17B10 | |
| SCHEMBL8022205 | 0.87 | KCNJ11 (0.41) | KCNJ11MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL3955070 | 0.86 | HSD17B10 (0.47) | MAPTALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL8023616 | 0.83 | KCNJ11 (0.40) | KCNJ11MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL8011621 | 0.81 | HSD11B1 (0.42) | KCNJ11CNR2MAPTALDH1A1HSD17B10 | |
| SCHEMBL27300614 | 0.79 | HSD17B10 (0.41) | KCNJ11MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL6418428 | 0.79 | HPRT1 (0.40) | KCNJ11MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL6420827 | 0.79 | CYP1A2 (0.37) | KCNJ11MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL7776439 | 0.77 | CYP1A2 (0.38) | CNR2MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL8010776 | 0.76 | KCNJ11 (0.39) | KCNJ11MAPTALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | claimed |
| US-7220884-B2 | Hydroaminomethylation of olefins | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| EP-1713757-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2006-10-25 | — | — | EP | disclosed |
| US-20050215825-A1 | Hydroaminomethylation of olefins | UNION CARBIDE CORPORATION | 2005-09-29 | — | — | US | disclosed |
| WO-2005077884-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215825-A1 | Hydroaminomethylation of olefins | HRH2, HRH4, HRH1 | KCNJ11 1181/4885CNR2 659/4885MAPT 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.