Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509954 | 0.89 | KCNJ11 (0.44) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6418428 | 0.84 | HPRT1 (0.40) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6420827 | 0.84 | CYP1A2 (0.37) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3955070 | 0.81 | HSD17B10 (0.47) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6419124 | 0.81 | CYP1A2 (0.38) | KCNJ11MAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8011621 | 0.80 | HSD11B1 (0.42) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8022205 | 0.79 | KCNJ11 (0.41) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8010776 | 0.78 | KCNJ11 (0.39) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8023616 | 0.75 | KCNJ11 (0.40) | KCNJ11MAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL6423409 | 0.74 | HPRT1 (0.40) | KCNJ11MAPTKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956133-B2 | Process for hydroformylating an olefin | OXENO OLEFINCHEMIE GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-6924389-B2 | Method for producing diphosphines and the use thereof | OXENO OLEFINCHEMIE GMBH (DE) | 2005-08-02 | — | — | US | disclosed |
| US-20050038272-A1 | Process for preparing diphosphines | OXENO OLEFINCHEMIE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040110979-A1 | Process for preparing diphosphines | EVONIK DEGUSSA GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110979-A1 | Process for preparing diphosphines | CYTH2, DOHH, HRH2 | P2RX1 1508/4885P2RX3 1721/4885P2RX4 1566/4885 |
| US-20050038272-A1 | Process for preparing diphosphines | HRH2, HRH3, HRH4 | P2RX1 549/4885P2RX3 646/4885P2RX4 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.