Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15360269 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HTTCCNE2CCNE1CDK2 | |
| SCHEMBL19848300 | 0.83 | CYP3A4 (0.36) | ALDH1A1HTTCCNE2CCNE1CDK2 | |
| SCHEMBL2841149 | 0.83 | KCNH3 (0.36) | ALDH1A1HTTCCNE2CCNE1CDK2 | |
| SCHEMBL306848 | 0.82 | HTT (0.50) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL1547786 | 0.82 | CA3 (0.42) | ALDH1A1HTTCCNE2CCNE1CDK2 | |
| SCHEMBL9230966 | 0.80 | MAPT (0.42) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL854924 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HTTCCNE2CCNE1CDK2 | |
| SCHEMBL26092148 | 0.80 | HTT (0.45) | ALDH1A1HTTPOLBMAPTTDP1 | |
| SCHEMBL19848697 | 0.80 | CHRNA7 (0.39) | MAPTTAAR1PKM | |
| SCHEMBL9232284 | 0.78 | CLCN2 (0.40) | ALDH1A1MEN1KMT2AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |