Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432303 | 0.87 | ARG1 (0.51) | ARG1GRM2GRM3GRIK1AGTR2 | |
| SCHEMBL11239409 | 0.87 | ARG1 (0.51) | ARG1GRM2GRM3GRIK1AGTR2 | |
| SCHEMBL11239411 | 0.87 | ARG1 (0.51) | ARG1GRM2GRM3GRIK1AGTR2 | |
| SCHEMBL5516614 | 0.86 | ARG1 (0.48) | ARG1GRIK1 | |
| SCHEMBL4862877 | 0.84 | ARG1 (0.48) | ARG1GRIK1 | |
| SCHEMBL11248416 | 0.83 | ARG1 (0.45) | ARG1GRIK1NPC1 | |
| SCHEMBL31524208 | 0.83 | HRH3 (0.55) | ARG1TAAR1HRH3GRIK1 | |
| SCHEMBL31080928 | 0.83 | HRH3 (0.55) | ARG1TAAR1HRH3GRIK1 | |
| SCHEMBL11234759 | 0.83 | HRH3 (0.55) | ARG1TAAR1HRH3GRIK1 | |
| SCHEMBL31080931 | 0.83 | HRH3 (0.55) | ARG1TAAR1HRH3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | claimed |
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-7164011-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1654268-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005007665-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2005-01-27 | — | — | WO | disclosed |