Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11245377 | 0.88 | ARG1 (0.36) | ARG1GRIK1MMP12MMP13MEN1 | |
| SCHEMBL11239411 | 0.84 | ARG1 (0.51) | ARG1GRIK1KDM4ESMN1; SMN2 | |
| SCHEMBL11239409 | 0.84 | ARG1 (0.51) | ARG1GRIK1KDM4ESMN1; SMN2 | |
| SCHEMBL19432303 | 0.84 | ARG1 (0.51) | ARG1GRIK1KDM4ESMN1; SMN2 | |
| SCHEMBL5516614 | 0.83 | ARG1 (0.48) | ARG1GRIK1ALDH1A1 | |
| SCHEMBL5510068 | 0.83 | ARG1 (0.48) | ARG1GRIK1NPC1 | |
| SCHEMBL4862877 | 0.81 | ARG1 (0.48) | ARG1GRIK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11243299 | 0.76 | ARG1 (0.54) | ARG1GRIK1KDM4E | |
| SCHEMBL11243295 | 0.76 | ARG1 (0.54) | ARG1GRIK1KDM4E | |
| SCHEMBL3787271 | 0.72 | ARG1 (0.60) | ARG1S1PR3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |