Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239411 | 1.00 | ARG1 (0.51) | ARG1KDM4EMAPTHIF1AAGTR2 | |
| SCHEMBL19432303 | 1.00 | ARG1 (0.51) | ARG1KDM4EMAPTHIF1AAGTR2 | |
| SCHEMBL11243295 | 0.91 | ARG1 (0.54) | ARG1KDM4EMAPTHIF1AGRIK1 | |
| SCHEMBL11243299 | 0.91 | ARG1 (0.54) | ARG1KDM4EMAPTHIF1AGRIK1 | |
| SCHEMBL4862877 | 0.87 | ARG1 (0.48) | ARG1MAPTGRIK1SMN1; SMN2 | |
| SCHEMBL5516614 | 0.87 | ARG1 (0.48) | ARG1GRIK1HDAC3HDAC4HDAC1 | |
| SCHEMBL5510068 | 0.87 | ARG1 (0.48) | ARG1AGTR2GRIK1GRM2GRM3 | |
| SCHEMBL11248416 | 0.84 | ARG1 (0.45) | ARG1KDM4EGRIK1SMN1; SMN2 | |
| SCHEMBL1706921 | 0.81 | HRH3 (0.54) | ARG1GRIK1F2 | |
| SCHEMBL22536533 | 0.81 | HRH3 (0.54) | ARG1GRIK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |