Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | PRKX | P51817 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815751 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1ALOX12MMP13LMNASMN1; SMN2 | |
| SCHEMBL1204743 | 0.82 | GAA (0.78) | ALDH1A1CYP2D6CYP2C9NPC1CYP1A2 | |
| SCHEMBL29194733 | 0.80 | SMN1; SMN2 (0.59) | ALDH1A1MMP13LMNASMN1; SMN2HPGD | |
| SCHEMBL3816981 | 0.79 | MMP13 (0.77) | ALDH1A1CYP2D6CYP2C9MMP13LMNA | |
| SCHEMBL13940425 | 0.79 | MMP13 (0.90) | ALDH1A1CYP2D6CYP2C9MMP13LMNA | |
| SCHEMBL7134254 | 0.79 | MMP13 (0.86) | ALDH1A1CYP2D6CYP2C9NPC1MMP13 | |
| SCHEMBL5517259 | 0.78 | POLB (0.74) | ALDH1A1ALOX12LMNASMN1; SMN2MEN1 | |
| SCHEMBL12069264 | 0.78 | POLB (0.78) | ALDH1A1CYP2D6CYP2C9NPC1CYP1A2 | |
| SCHEMBL31396722 | 0.78 | MMP13 (0.75) | ALDH1A1CYP2D6CYP2C9MMP13LMNA | |
| SCHEMBL5332456 | 0.78 | MMP13 (0.89) | ALDH1A1CYP2D6CYP2C9NPC1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | claimed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | claimed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | claimed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | claimed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | disclosed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885CYP2D6 688/4885CYP2C9 619/4885 |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885CYP2D6 688/4885CYP2C9 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.