SCHEMBL5510282

SCHEMBL5510282

Oc1c(F)cc(F)c(F)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.40
CA2 P00918 3/20 0.40
CA4 P22748 2/20 0.40
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ERN1 O75460 1/20 0.36
CA12 O43570 2/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CA9 Q16790 2/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PTPN11 Q06124 1/20 0.31
SELL P14151 1/20 0.30
SELP P16109 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78211 0.87 CA1 (0.43) CA1CA2CA4CES2CES1
SCHEMBL2396959 0.81 CA1 (0.40) CA1CA2CA4CES2CES1
SCHEMBL30367972 0.81 CA1 (0.40) CA1CA2CA4CES2CES1
SCHEMBL516135 0.80 ERN1 (0.39) CA1CA2CA4CES2CES1
Cyanide SCHEMBL28063240 0.79 CA1 (0.39) CA1CA2CA4CES2CES1
SCHEMBL5514095 0.75 CES2 (0.38) CA1CA2CA4CES2CES1
SCHEMBL25475667 0.75 CA1 (0.36) CA1CA2CA4CES2CES1
SCHEMBL8119023 0.75 ERN1 (0.37) CA1CA2CA4CES2CES1
SCHEMBL19542052 0.75 CES2 (0.39) CA1CA2CA4CES2CES1
SCHEMBL9027960 0.75 HSD17B10 (0.38) CA1CA2CA4CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed