SCHEMBL516135

SCHEMBL516135

Oc1c(F)cc(F)c(O)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.39
CA1 P00915 4/20 0.38
CA2 P00918 3/20 0.38
CA4 P22748 2/20 0.38
CA9 Q16790 2/20 0.35
CA12 O43570 2/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367972 0.87 CA1 (0.40) ERN1CA1CA2CA4CA9
SCHEMBL2396959 0.87 CA1 (0.40) ERN1CA1CA2CA4CA9
SCHEMBL5510282 0.80 CA1 (0.40) ERN1CA1CA2CA4CA9
SCHEMBL11591491 0.80 VRK1 (0.38) ERN1SELLSELPSELEVRK1
SCHEMBL14430166 0.80 CA1 (0.43) ERN1CA1CA2ESR1ESR2
SCHEMBL24040793 0.80 SELL (0.38) ERN1CA1CA2CA4SELL
SCHEMBL7861083 0.80 ERN1 (0.32) ERN1
SCHEMBL78211 0.79 CA1 (0.43) ERN1CA1CA2CA4CA9
SCHEMBL5948999 0.78 ERN1 (0.34) ERN1CA1CA9CA12CA3
SCHEMBL67874 0.78 CA3 (0.36) ERN1CA9CA3CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137551-B1 FIBER REINFORCED POLYETHERIMIDE COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2024-08-07 EP disclosed
EP-3592724-B1 PROCESSES FOR THE PREPARATION OF HALO SUBSTITUTED BENZOIC ACID COMPOUNDS SRF LTD (IN) 2023-05-10 EP disclosed
US-10626074-B2 Process for preparation of halo substituted benzoic acid compound and intermediates thereof SRF LIMITED (IN) 2020-04-21 US disclosed
EP-2935695-B1 ELECTRICAL INSULATION PAPER, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-04 EP disclosed
CN-106459412-B Fibre-reinforced polyetherimide compositions 沙特基础工业全球技术公司 2019-07-30 CN disclosed
US-20180162086-A1 HONEYCOMB PAPER SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-06-14 US disclosed
US-9994710-B2 Fiber reinforced polyetherimide compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-12 US disclosed
EP-3302956-A1 HONEYCOMB PAPER SABIC Global Technologies B.V. (NL) 2018-04-11 EP disclosed
CN-107848239-A Honeycomb paper 沙特基础工业全球技术有限公司 2018-03-27 CN disclosed
CN-104169482-B Electrically-insulating paper, manufacture method and the product being produced from it 沙特基础全球技术有限公司 2017-11-17 CN disclosed
WO-2008134340-A1 POLYESTER POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-06 WO disclosed
US-20080269386-A1 POLYESTER POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-10-30 US disclosed
US-20080269399-A1 POLYESTER POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-10-30 US disclosed
US-20080269400-A1 POLYESTER POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-10-30 US disclosed
WO-2008063724-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO disclosed
WO-2008063723-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO disclosed
WO-2008063722-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO disclosed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-20080119597-A1 Blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-20080119596-A1 Transparant blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626074-B2 Process for preparation of halo substituted benzoic acid compound and intermediates thereof CYP1B1, SULT1A1, CYP1A1 ERN1 1600/4885CA1 259/4885CA2 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.