SCHEMBL2396959

SCHEMBL2396959

Oc1c(F)cc(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.40
CA2 P00918 3/20 0.40
CA4 P22748 2/20 0.40
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ERN1 O75460 1/20 0.36
CA12 O43570 2/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CA9 Q16790 2/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
SELL P14151 1/20 0.30
SELP P16109 1/20 0.30
SELE P16581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367972 1.00 CA1 (0.40) CA1CA2CA4CES2CES1
SCHEMBL516135 0.87 ERN1 (0.39) CA1CA2CA4CES2CES1
SCHEMBL5510282 0.81 CA1 (0.40) CA1CA2CA4CES2CES1
SCHEMBL5509678 0.81 CES2 (0.38) CA1CA2CA4CES2CES1
SCHEMBL78211 0.80 CA1 (0.43) CA1CA2CA4CES2CES1
SCHEMBL67874 0.79 CA3 (0.36) ERN1CA9CA3CA6CA5A
SCHEMBL5948999 0.79 ERN1 (0.34) CA1CES2CES1ERN1CA12
SCHEMBL12459470 0.77 CA1 (0.37) CA1CA2CA4CES2CES1
SCHEMBL11432827 0.76 ERN1 (0.39) ERN1ESR1ESR2
SCHEMBL5948336 0.76 PTGES (0.34) CES2CES1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 US disclosed
US-20250108124-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS BIOHAVEN THERAPEUTICS LTD (US) 2025-04-03 US disclosed
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-118852275-A Titanium-metallocene catalyst and preparation method and application thereof 中山大学 2024-10-29 CN disclosed
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
WO-2024175999-A2 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF DUNAD THERAPEUTICS LTD. (GB) 2024-08-29 WO disclosed
EP-4402133-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS Enko Chem, Inc. (US) 2024-07-24 EP disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
CN-118265704-A Protoporphyrinogen oxidase inhibitors 恩科化学公司 2024-06-28 CN disclosed
EP-4340859-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS Biohaven Therapeutics Ltd. (US) 2024-03-27 EP disclosed
WO-2003084982-A2 FUNCTIONALIZED COMPOSITIONS FOR IMPROVED IMMOBILIZATION LUMINEX CORPORATION (US) 2003-10-16 WO disclosed
US-5248745-A Copolymerization of dicyclopentadiene with norbornene derivatives SHELL OIL COMPANY (US) 1993-09-28 US disclosed
US-5180867-A COPOLYMERIZATION OF DICYCLOPENTADIENE WITH NORBORNENE DERIVATIVES SHELL OIL COMPANY (US) 1993-01-19 US disclosed
US-5093441-A POLYMERIZATION OF NORBORNENE DERIVATIVES SHELL OIL COMPANY (US) 1992-03-03 US disclosed
US-5081208-A Using a catalyst system comprising the reaction product of a tungsten compound and a halo- or trihalomethylphenol and a trihydrocarbyltin hydride; RIM; kinetics SHELL OIL COMPANY (US) 1992-01-14 US disclosed
US-4994426-A Catalyst and process for polymerization of norbornene derivatives SHELL OIL COMPANY (US) 1991-02-19 US disclosed
EP-0385556-A2 Polymerization of bulky norbornene derivatives and polymers obtainable therewith SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-09-05 EP disclosed
EP-0372600-A2 Copolymerization of dicyclopentadiene with norbornene derivatives and copolymers obtainable therewith SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-13 EP disclosed
US-4897255-A Metal radionuclide labeled proteins for diagnosis and therapy NEORX CORPORATION (US) 1990-01-30 US disclosed
EP-0336486-A2 Polymerization of norbornene derivatives and catalytic system suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108124-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS CD47, DOCK2, DOCK5 CA1 1855/4885CA2 2542/4885CA4 1688/4885
US-12637438-B2 Protoporphyrinogen oxidase inhibitors PPOX, CYP4X1, CBR3 CA1 1168/4885CA2 288/4885CA4 899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.