Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MYOC | Q99972 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317292 | 0.89 | KMT2A (0.66) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL3897213 | 0.89 | MEN1 (0.72) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3452251 | 0.87 | KMT2A (0.64) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL5510635 | 0.83 | ALDH1A1 (0.68) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL3900126 | 0.81 | KMT2A (0.57) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL5509037 | 0.81 | MAPT (0.56) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL6302417 | 0.80 | MEN1 (0.89) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL6302157 | 0.78 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTPOLB | |
| SCHEMBL1177730 | 0.78 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTPOLB | |
| SCHEMBL2026125 | 0.76 | MAPT (0.65) | MEN1KMT2ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203117-A1 | modulators of nicotinic and/or of monoamine receptors; as diagnostic tools or monitoring agents; for in vivo neuroimaging in labeled/unlabelled forms; inflammation, pain, neurodegenerative disorders; cholinergic ligands;5-(4-Benzoylamino-phenyl)-furan-2-carboxylic acid(1-aza-bicyclo[2.2.2]oct-3-yl)-amide | NEUROSEARCH A/S (DK) | 2007-08-30 | — | — | US | claimed |
| EP-1751150-A2 | NOVEL AZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2007-02-14 | — | — | EP | claimed |
| WO-2005111033-A2 | NOVEL AZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-11-24 | — | — | WO | claimed |
| US-20070203117-A1 | modulators of nicotinic and/or of monoamine receptors; as diagnostic tools or monitoring agents; for in vivo neuroimaging in labeled/unlabelled forms; inflammation, pain, neurodegenerative disorders; cholinergic ligands;5-(4-Benzoylamino-phenyl)-furan-2-carboxylic acid(1-aza-bicyclo[2.2.2]oct-3-yl)-amide | NEUROSEARCH A/S (DK) | 2007-08-30 | — | — | US | disclosed |
| EP-1751150-A2 | NOVEL AZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111033-A2 | NOVEL AZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203117-A1 | modulators of nicotinic and/or of monoamine receptors; as diagnostic tools or monitoring agents; for in vivo neuroimaging in labeled/unlabelled forms; inflammation, pain, neurodegenerative disorders; cholinergic ligands;5-(4-Benzoylamino-phenyl)-furan-2-carboxylic acid(1-aza-bicyclo[2.2.2]oct-3-yl)-amide | CHRNA5, CHRNA2, CHRNA6 | MEN1 3680/4885KMT2A 2233/4885NPC1 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.