SCHEMBL5510952

SCHEMBL5510952

CCCCCCCCCCCCCCCCc1ccccc1Oc1ccccc1CCCCCCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.58
THRB P10828 1/20 0.58
LIPG Q9Y5X9 1/20 0.56
ALOX5 P09917 1/20 0.54
PTGS2 P35354 1/20 0.54
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.49
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
BID P55957 1/20 0.44
BCL2L1 Q07817 1/20 0.44
MCL1 Q07820 1/20 0.44
BAK1 Q16611 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30432172 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL3762716 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL145217 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL29626147 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL173283 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL8052297 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL941553 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL93801 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL9505410 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL8444310 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030070548-A1 Polymer material, surfactant and a hydrophilic compound that is not a polymer; detection of glucose, lactate, urea or creatinine RADIOMETER MEDICAL APS (DK) 2003-04-17 US claimed
EP-1292823-A1 A SENSOR MEMBRANE, A METHOD FOR THE PREPARATION THEREOF, A SENSOR AND A LAYERED MEMBRANE STRUCTURE FOR SUCH SENSOR RADIOMETER MEDICAL A/S (DK) 2003-03-19 EP claimed
WO-2001090733-A1 A SENSOR MEMBRANE, A METHOD FOR THE PREPARATION THEREOF, A SENSOR AND A LAYERED MEMBRANE STRUCTURE FOR SUCH SENSOR RADIOMETER MEDICAL A/S (DK) 2001-11-29 WO claimed
EP-0492556-B1 Continuous process for the preparation of isocyanates ENICHEM SINTESI (IT) 1994-12-07 EP claimed
EP-0492556-A1 Continuous process for the preparation of isocyanates ENICHEM SYNTHESIS S.p.A. (IT) 1992-07-01 EP claimed
EP-0220576-B1 STAINPROOF POLYESTER FIBER TEIJIN LIMITED (JP) 1991-01-02 EP claimed
EP-4149415-B1 SHAMPOO COMPOSITION COMPRISING ALKYL GLUCOSIDE PROCTER & GAMBLE (US) 2026-05-20 EP disclosed
US-12605326-B2 Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant L'OREAL (FR) 2026-04-21 US disclosed
EP-4337333-B1 SHAMPOO COMPOSITION PROCTER & GAMBLE (US) 2026-04-15 EP disclosed
US-12589065-B2 Hair care system, hair care method and use of a hair care system L'OREAL (FR) 2026-03-31 US disclosed
EP-4149416-B1 SHAMPOO COMPOSITION COMPRISING DECYL GLUCOSIDE AND A CATIONIC GUAR PROCTER & GAMBLE (US) 2026-01-21 EP disclosed
US-20240383810-A1 SILICON COMPOSITION AND ITS APPLICATION AS AN ADDITIVE FOR REDUCING WATER UPTAKE ENHANCING COMPRESSIVE STRENGTH IN CEMENT INDUSTRY WACKER METROARK CHEMICALS PVT. LTD. (IN) 2024-11-21 US disclosed
US-12138339-B2 Dye composition based on copolymers derived from the polymerization of at least one crotonic acid monomer or crotonic acid derivative and on silicone L'OREAL (FR) 2024-11-12 US disclosed
US-7195697-B2 Polymer material, surfactant and a hydrophilic compound that is not a polymer; detection of glucose, lactate, urea or creatinine RADIOMETER MEDICAL A/S (DK) 2007-03-27 US disclosed
US-20030070548-A1 Polymer material, surfactant and a hydrophilic compound that is not a polymer; detection of glucose, lactate, urea or creatinine RADIOMETER MEDICAL APS (DK) 2003-04-17 US disclosed
EP-1292823-A1 A SENSOR MEMBRANE, A METHOD FOR THE PREPARATION THEREOF, A SENSOR AND A LAYERED MEMBRANE STRUCTURE FOR SUCH SENSOR RADIOMETER MEDICAL A/S (DK) 2003-03-19 EP disclosed
WO-2001090733-A1 A SENSOR MEMBRANE, A METHOD FOR THE PREPARATION THEREOF, A SENSOR AND A LAYERED MEMBRANE STRUCTURE FOR SUCH SENSOR RADIOMETER MEDICAL A/S (DK) 2001-11-29 WO disclosed
EP-0492556-B1 Continuous process for the preparation of isocyanates ENICHEM SINTESI (IT) 1994-12-07 EP disclosed
US-5210284-A CONTINUOUS PROCESS FOR THE PREPARATION OF ISOCYANATES FROM URETHANES ENICHEM SYNTHESIS S.P.A. (IT) 1993-05-11 US disclosed
EP-0492556-A1 Continuous process for the preparation of isocyanates ENICHEM SYNTHESIS S.p.A. (IT) 1992-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589065-B2 Hair care system, hair care method and use of a hair care system ASH2L, ALG3, PLOD3 THRA 1923/4885THRB 903/4885LIPG 2664/4885
US-12605326-B2 Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant MSH6, KRT18, MMAB THRA 190/4885THRB 197/4885LIPG 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.