Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494360 | 0.86 | KDM4E (0.41) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5515014 | 0.81 | MEN1 (0.61) | TSHRSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL5524440 | 0.79 | TSHR (0.58) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3189623 | 0.77 | CA1 (0.60) | KDM4EUSP2TSHRALDH1A1CA1 | |
| SCHEMBL5513651 | 0.77 | KDM4E (0.50) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3189633 | 0.77 | CA1 (0.60) | KDM4EUSP2TSHRALDH1A1CA1 | |
| SCHEMBL4592297 | 0.77 | CA1 (0.60) | KDM4EUSP2TSHRALDH1A1CA1 | |
| SCHEMBL4020740 | 0.75 | TSHR (0.66) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5922866 | 0.74 | TSHR (0.56) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5922867 | 0.74 | TSHR (0.56) | KDM4EUSP2TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060189771-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060041092-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |