Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774489 | 0.82 | CCR3 (0.42) | CCR3MCHR1 | |
| SCHEMBL6000402 | 0.79 | MCHR1 (0.51) | CCR3MCHR1 | |
| SCHEMBL4792335 | 0.78 | DRD2 (0.51) | MCHR1ADRA1A | |
| SCHEMBL4764957 | 0.77 | — | — | |
| SCHEMBL4767852 | 0.76 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5515572 | 0.72 | MCHR1 (0.47) | MCHR1ADRA1DADRA1AADRA1B | |
| SCHEMBL5520326 | 0.71 | ADRA1D (0.47) | ADRA1DADRA1AADRA1B | |
| SCHEMBL4768052 | 0.71 | DRD2 (0.48) | ADRA1A | |
| SCHEMBL4765113 | 0.71 | ADRA1A (0.48) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5511219 | 0.69 | DRD2 (0.46) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199135-B2 | Substituted alkyl amido piperidines | H. LUNDBECK A/S (DK) | 2007-04-03 | — | — | US | disclosed |
| US-20060084649-A9 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084649-A9 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | CCR3 485/4885MCHR1 1/4885ADRA1D 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.