Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180507 | 0.82 | MAPK1 (0.44) | MAPK1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4405908 | 0.80 | RAB9A (0.61) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4179964 | 0.77 | MAPK1 (0.43) | MAPK1MAPTL3MBTL1TRPV1SMN1; SMN2 | |
| SCHEMBL12394470 | 0.74 | ALDH1A1 (0.63) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4265054 | 0.72 | SMN1; SMN2 (0.69) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4411938 | 0.71 | RAB9A (0.57) | L3MBTL1RAB9ANPC1ALDH1A1CYP1A2 | |
| SCHEMBL5503548 | 0.71 | KMT2A (0.54) | SMN1; SMN2LMNATSHR | |
| SCHEMBL17678911 | 0.71 | TRPV1 (0.43) | TRPV1ALDH1A1LMNATSHR | |
| SCHEMBL13947396 | 0.70 | SMN1; SMN2 (0.54) | MAPK1L3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4403796 | 0.70 | RAB9A (0.56) | L3MBTL1TRPV1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828162-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006061706-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-15 | — | — | WO | disclosed |