Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512431 | 1.00 | LPAR1 (0.53) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL6700873 | 0.93 | PRKD3 (0.48) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL8638519 | 0.93 | PRKD3 (0.48) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL8004701 | 0.91 | PLA2G2A (0.51) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL8004697 | 0.91 | PLA2G2A (0.51) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL25208892 | 0.86 | P2RY10 (0.47) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL2217519 | 0.86 | P2RY10 (0.47) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL2231310 | 0.86 | P2RY10 (0.47) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL2217525 | 0.86 | P2RY10 (0.47) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL1967093 | 0.86 | P2RY10 (0.47) | LPAR1LPAR3PLA2G2APLA2G10PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259273-B1 | Compositions containing lysophosphotidic acids which inhabit apoptosis and uses thereof | GODDARD JOHN G | 2007-08-21 | — | — | US | disclosed |
| EP-1024812-B1 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | SKY HIGH LLC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20060063738-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC (US) | 2006-03-23 | — | — | US | disclosed |
| US-6949528-B1 | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof | GODDARD JOHN G | 2005-09-27 | — | — | US | disclosed |
| US-6949529-B2 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC (US) | 2005-09-27 | — | — | US | disclosed |
| US-20030149002-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC. | 2003-08-07 | — | — | US | disclosed |
| US-6495532-B1 | PRESERVATION AND TREATMENT OF ORGANS FOR TRANSPLANTATION WITH SUCH AS 3-OLEOYL-2-METHYL-1-THIOPHOSPHATE-GLYCERIDE AND A POTENTIATING COPONENT SUCH AS POLYETHYLENE GLYCOL, A PROTEIN OR A LIPID MEMBRANE | SKY HIGH, LLC | 2002-12-17 | — | — | US | disclosed |
| US-6380177-B1 | EXPOSING THE CELL TO AN EDG2 RECEPTOR ACTIVATING COMPOUND SUCH AS 3-O-OLEOYL-2-O-METHYL-RAC-GLYCERO-1-PHOSPHATE OR 1-O-OLEOYL-2-O-METHYL-RAC-GLYCEROL FOR ACTIVATING RECEPTOR | ATAIRGIN TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063738-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | LPAR5, LPAR2, LPAR6 | LPAR1 4/4885LPAR3 5/4885PLA2G2A 25/4885 |
| US-20030149002-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | LPAR5, LPAR2, LPAR6 | LPAR1 4/4885LPAR3 5/4885PLA2G2A 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.