SCHEMBL5512440

SCHEMBL5512440

CCCOc1ccc(N=C2C=CC(=O)C(Cl)=C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.40
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LTA4H P09960 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PLK1 P53350 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.35
TSHR P16473 2/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518564 0.84 CA12 (0.44) CYP2C9CA12CA1CA2CA7
SCHEMBL15018778 0.76 TRPV4 (0.30)
SCHEMBL5530250 0.74 ALDH1A1 (0.45) CYP2C9CA12CA1CA2CA7
SCHEMBL15037502 0.69 MEN1 (0.35) CYP2C9MEN1KMT2AALDH1A1MAPT
SCHEMBL28964336 0.68 CYP2C9 (0.58) CYP2C9CA12CA1CA2CA7
SCHEMBL28964335 0.68 CYP2C9 (0.58) CYP2C9CA12CA1CA2CA7
1,4-Dipropoxybenzene SCHEMBL122039 0.67 LTA4H (0.67) CYP2C9CA12CA1CA2CA7
SCHEMBL257325 0.66 MEN1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL13808346 0.65 LTA4H (0.64) CYP2C9CA12CA1CA2CA7
SCHEMBL21699869 0.65 CYP2C9 (0.54) CYP2C9CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3928070-B2 2007-06-13 JP claimed
EP-0767809-A2 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-04-16 EP claimed
WO-1996000745-A2 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-11 WO claimed