Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997893 | 0.78 | VCP (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4138684 | 0.78 | TDP1 (0.38) | ALDH1A1KDM4EMEN1KMT2AMCOLN3 | |
| SCHEMBL5508919 | 0.73 | KDM4E (0.52) | ALDH1A1KDM4EMEN1KMT2AMCOLN3 | |
| SCHEMBL5634757 | 0.73 | GSK3B (0.46) | KDM4EMEN1KMT2AMAPTGSK3B | |
| SCHEMBL5531315 | 0.72 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1KMT2AMCOLN3 | |
| SCHEMBL5512259 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2AMCOLN3 | |
| SCHEMBL15329668 | 0.71 | AHR (0.50) | KDM4EMEN1KMT2AMAPTFNTA | |
| SCHEMBL5512640 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AMCOLN3 | |
| SCHEMBL6052699 | 0.69 | GSK3B (0.46) | KDM4EMEN1KMT2AMAPTGSK3B | |
| SCHEMBL5512695 | 0.69 | BRD4 (0.53) | ALDH1A1MAPTALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844011-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081343-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-03 | — | — | WO | disclosed |