Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997893 | 0.84 | VCP (0.45) | BRD4KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5512691 | 0.78 | ALDH1A1 (0.39) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5510992 | 0.73 | ALDH1A1 (0.55) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2880986 | 0.69 | BRD4 (0.57) | TDP1BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL5531315 | 0.68 | ALDH1A1 (0.65) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5508919 | 0.67 | KDM4E (0.52) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4890491 | 0.67 | HPGD (0.56) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| Tert-Butyl Formate SCHEMBL27699524 | 0.66 | ALDH1A1 (0.46) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5512259 | 0.65 | ALDH1A1 (0.46) | MCOLN3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL27964725 | 0.64 | ACHE (0.54) | MEN1ALDH1A1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066628-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008014186-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |