SCHEMBL5512893

SCHEMBL5512893

C=C(C(=O)OC1CCOC1=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.42
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 4/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
ATM Q13315 1/20 0.37
GAA P10253 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23509950 0.87 POLB (0.39) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL16372900 0.85 MAPK1 (0.41) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL18793086 0.84 POLB (0.45) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL14523973 0.83 POLB (0.46) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL70883 0.80 MAPK1 (0.49) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL19012506 0.80 MAPK1 (0.49) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL25358238 0.80 POLB (0.46) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL15246711 0.79 MAPK1 (0.41) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL27047573 0.79 POLB (0.44) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1
SCHEMBL5530696 0.78 ALDH1A1 (0.42) POLBKDM4ESMN1; SMN2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9395625-B2 Acrylic acid ester derivative and method for producing same, intermediate and method for producing same, high-molecular-weight compound, and photoresist composition KURARAY CO., LTD. (JP) 2016-07-19 US disclosed
US-9395625-B2 Acrylic acid ester derivative and method for producing same, intermediate and method for producing same, high-molecular-weight compound, and photoresist composition KURARAY CO., LTD. (JP) 2016-07-19 US disclosed
US-9104105-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-11 US disclosed
US-9104105-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-11 US disclosed
US-20150037733-A1 ACRYLIC ACID ESTER DERIVATIVE AND METHOD FOR PRODUCING SAME, INTERMEDIATE AND METHOD FOR PRODUCING SAME, HIGH-MOLECULAR-WEIGHT COMPOUND, AND PHOTORESIST COMPOSITION KURARAY CO., LTD. (JP) 2015-02-05 US disclosed
US-20150037733-A1 ACRYLIC ACID ESTER DERIVATIVE AND METHOD FOR PRODUCING SAME, INTERMEDIATE AND METHOD FOR PRODUCING SAME, HIGH-MOLECULAR-WEIGHT COMPOUND, AND PHOTORESIST COMPOSITION KURARAY CO., LTD. (JP) 2015-02-05 US disclosed
EP-2821403-A1 ACRYLIC ACID ESTER DERIVATIVE AND METHOD FOR PRODUCING SAME, INTERMEDIATE AND METHOD FOR PRODUCING SAME, HIGH-MOLECULAR-WEIGHT COMPOUND, AND PHOTORESIST COMPOSITION Kuraray Co., Ltd. (JP) 2015-01-07 EP disclosed
US-8846295-B2 Photoresist composition containing a protected hydroxyl group for negative development and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-09-30 US disclosed
US-8846295-B2 Photoresist composition containing a protected hydroxyl group for negative development and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-09-30 US disclosed
US-20140242518-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-28 US disclosed
US-20080038676-A1 TOP COAT MATERIAL AND USE THEREOF IN LITHOGRAPHY PROCESSES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-02-14 US disclosed
WO-2007121456-A2 WET DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND METHOD FOR USE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-10-25 WO disclosed
US-20070243484-A1 Wet developable bottom antireflective coating composition and method for use thereof GLOBALFOUNDRIES U.S. INC. 2007-10-18 US disclosed
US-20070243484-A1 Wet developable bottom antireflective coating composition and method for use thereof GLOBALFOUNDRIES U.S. INC. 2007-10-18 US disclosed
US-20070231736-A1 Bottom antireflective coating composition and method for use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION 2007-10-04 US disclosed
US-20070231736-A1 Bottom antireflective coating composition and method for use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION 2007-10-04 US disclosed
US-20070083021-A1 Fluorocopolymer, method for its production and resist composition containing it ASAHI GLASS COMPANY, LIMITED (JP) 2007-04-12 US disclosed
US-20070083021-A1 Fluorocopolymer, method for its production and resist composition containing it ASAHI GLASS COMPANY, LIMITED (JP) 2007-04-12 US disclosed
US-20060058480-A1 Polymerizable monomer polymeric compound resin compositions for photoresist and method for producing semiconductor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
US-20050282985-A1 FLUORINE-ATOM-CONTAINING POLYMERIZABLE UNSATURATED-MONOMER, FLUORINE-ATOM-CONTAINING POLYMERIC COMPOUND AND PHOTORESIST RESIN COMPOSITION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282985-A1 FLUORINE-ATOM-CONTAINING POLYMERIZABLE UNSATURATED-MONOMER, FLUORINE-ATOM-CONTAINING POLYMERIC COMPOUND AND PHOTORESIST RESIN COMPOSITION AFF1, AFF2, FPR1 POLB 2358/4885KDM4E 2078/4885SMN1; SMN2 3124/4885
US-20150037733-A1 ACRYLIC ACID ESTER DERIVATIVE AND METHOD FOR PRODUCING SAME, INTERMEDIATE AND METHOD FOR PRODUCING SAME, HIGH-MOLECULAR-WEIGHT COMPOUND, AND PHOTORESIST COMPOSITION GFER, ASH2L, MLLT1 POLB 2592/4885KDM4E 991/4885SMN1; SMN2 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.