SCHEMBL5513073

SCHEMBL5513073

CNc1ccc2cc(N)c(F)c(F)c2c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.34
TERT O14746 1/20 0.34
HTR6 P50406 1/20 0.33
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511618 0.79 MAPK14 (0.35) EGFRTERTHTR6APP
SCHEMBL5514136 0.75 SLC18A1 (0.34) TERT
SCHEMBL27620147 0.75 HTR6 (0.38) EGFRTERTHTR6APP
SCHEMBL5510016 0.75 MEN1 (0.41) EGFR
SCHEMBL5514270 0.73 CA12 (0.33)
SCHEMBL5507077 0.73 EGFR (0.35) EGFRHTR6APP
SCHEMBL5514423 0.72 ESR1 (0.46)
SCHEMBL6586122 0.70 F2 (0.49) EGFRTERT
SCHEMBL5509816 0.70 PRKCI (0.34)
SCHEMBL5511612 0.69 ALDH1A1 (0.50) EGFRAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed